Singapore Institute for Clinical Sciences (SICS)

Singaporean Chinese, Malays and Indians produce different insulin responses to a bowl of rice

An oral antidiabetic drug shows promise for treating tuberculosis

A detailed study of infants and mothers before and after birth provides valuable insights

A fluorescent probe for labeling mitochondria helps scientists study fat-burning brown adipose tissue

Depression in pregnant women is associated with low folate levels, but not with vitamin B12

Abnormalities within muscle signaling pathways, rather than body fat distribution, may influence insulin resistance among South Asians

A protein known as seipin regulates fat development through cytoskeleton remodeling

Manipulating a population of blood cells in an individual could help to activate immune responses against the hepatitis B virus

A newly discovered subset of white blood cells in mice and humans could improve treatments for infections and autoimmune diseases

Contrary to conventional wisdom, exposure to the hepatitis B virus activates immunity in young people, suggesting benefits for earlier treatment

Recently uncovered human counterparts to a subset of mouse immune cells may enable better vaccination strategies

Gene therapy restores adaptive immunity in patients with chronic hepatitis B and directs T cells to tumor cells in patients with hepatitis B virus-related hepatocellular carcinoma