Stem cells

Researchers use single-cell sequencing for a new look at how stem cell-derived retinal cells fare after transplants for degenerative eye disorders.

A*STAR researchers challenge existing theories around intestinal stem cell biology using a newly developed animal model of intestinal regeneration.

Researchers have identified a stem cell marker that influences fat cell development, unlocking exciting therapeutic opportunities for chronic diseases.

New data suggest that metformin administered to pregnant mothers may have unintended effects on the fetus, prompting the need for further assessment of the drug’s risk-benefit ratio.

A breakthrough stem cell transplant technology uses donated cadaver eyes to restore vision in patients with retinal degeneration.

New research techniques are enabling scientists like SIgN’s Florent Ginhoux to unravel the complexities of the immune system like never before.

A*STAR researchers have created the first machine learning model for predicting clinical outcomes of stem cell therapies in patients with cartilage disorders.

Scientists identify a key molecular marker of muscle stem cells, providing novel insights into the mechanisms around muscle regeneration.

When placed in the proper environment, even stem cells from unlikely sources like the bladder or prostate can form skin components like hair follicles and sebaceous glands.

Low levels of sugar entering into pancreatic cells may be the culprit behind insulin secretion defects in early-onset diabetes.

Single-cell techniques have helped to identify a key molecular switch controlling how adult cells can be turned back to a stem cell-like state.

For the first time, researchers have generated lab-grown livers that have functioning bile canaliculi, an important step towards modeling complex liver diseases.