Healing in the small intestine, redefined10 May 2022
A*STAR researchers challenge existing theories around intestinal stem cell biology using a newly developed animal model of intestinal regeneration.
Searching for good fat’s origins14 Feb 2022
Researchers have identified a stem cell marker that influences fat cell development, unlocking exciting therapeutic opportunities for chronic diseases.
A closer look at metformin in maternal diabetes25 Jan 2022
New data suggest that metformin administered to pregnant mothers may have unintended effects on the fetus, prompting the need for further assessment of the drug’s risk-benefit ratio.
Donor tissues provide the gift of sight24 Dec 2021
A breakthrough stem cell transplant technology uses donated cadaver eyes to restore vision in patients with retinal degeneration.
Tracing immune cells to their source20 Dec 2021
New research techniques are enabling scientists like SIgN’s Florent Ginhoux to unravel the complexities of the immune system like never before.
AI makes stem cells less unpredictable28 Oct 2021
A*STAR researchers have created the first machine learning model for predicting clinical outcomes of stem cell therapies in patients with cartilage disorders.
Unboxing the muscle repair toolkit20 Sep 2021
Scientists identify a key molecular marker of muscle stem cells, providing novel insights into the mechanisms around muscle regeneration.
A surprising new source for skin stem cells14 Jul 2021
When placed in the proper environment, even stem cells from unlikely sources like the bladder or prostate can form skin components like hair follicles and sebaceous glands.
Opening the cellular gates to glucose2 Jul 2021
Low levels of sugar entering into pancreatic cells may be the culprit behind insulin secretion defects in early-onset diabetes.
Sifting out rare stem cells14 Jun 2021
Single-cell techniques have helped to identify a key molecular switch controlling how adult cells can be turned back to a stem cell-like state.
A recipe for mini livers23 Apr 2021
For the first time, researchers have generated lab-grown livers that have functioning bile canaliculi, an important step towards modeling complex liver diseases.
Shaping 3D-printed bones for better implants5 Mar 2021
Porous metallic bones designed to be 3D-printed in unusual shapes could be the future of permanent orthopedic implants.