Stem cells

For the first time, researchers have generated lab-grown livers that have functioning bile canaliculi, an important step towards modeling complex liver diseases.

Porous metallic bones designed to be 3D-printed in unusual shapes could be the future of permanent orthopedic implants.

A novel genomic biomarker may help to meet the demand for donor mesenchymal stem cells in regenerative medicine.

From genomics to gene editing and cancer research, the A*STAR winners of the 2020 President’s Science and Technology Awards and Young Scientist Awards are blazing the trail in biological research.

Modifying how embryonic stem cells use sugar can switch them into a totipotent state, A*STAR researchers say.

A*STAR scientists have identified stem cells required for successful embryo implantation during pregnancy.

If cell-based therapies are to make it to the clinic, methods to grow stem cells in vast quantities will need to be developed. Here’s how A*STAR scientists are tackling the challenge of manufacturing stem cells at scale.

Microfluidic device allows for precise control of growth factor gradients, mimicking natural spinal cord development in vitro.

A dual-function protein switch can be tweaked to improve the effectiveness of cellular reprogramming

Stem cells that can produce both major lung tissue types have been isolated and can now repair the damaged lungs of mice

Genetic switch activates transformation of stem cells into heart muscle cells

A new method for making specialized immune cells
from stem cells offers a tool for modeling inflammatory diseases in the lab