A*STAR Bioinformatics Institute (A*STAR BII)

Scientists at A*STAR have found that a mutation in SARS-CoV-2 called ∆382 leads to milder clinical outcomes, with implications for COVID-19 treatments and vaccines.

Two early cases of COVID-19 in Thailand represent the first confirmed exported cases from China, a Thai-Singapore team reports.

In a display of scientific willpower, A*STAR researchers developed and deployed the COVID-19 diagnostic Fortitude Kit within weeks of the virus reaching Singapore’s shores.

A*STAR scientists aim to design better immunotherapies by simulating the binding of antibodies to their targets.

A*STAR scientists have identified drug compounds that could potentially eradicate an aggressive form of liver cancer by targeting a metabolic vulnerability induced by the SALL4 oncogene.

A better understanding of the way sugar units are attached to the surface proteins of cancer cells may help to improve targeted cancer treatments, A*STAR scientists say.

A*STAR researchers have identified specific sites in the surface protein of influenza viruses that allow the pathogen to adapt to different host organisms.

Researchers at A*STAR have combined two superresolution microscopy techniques to observe structural protein dynamics inside cells.

Short- and long-range interactions that give structure to virus genomes also influence virus replication and infectiousness.

Need to monitor how well a wound is healing? There’s an app for that.

An automated machine learning system for analyzing leg movements in fruit flies is helping A*STAR researchers shed light on how neurodegenerative diseases develop.

The host immune system has a limited impact on the evolution of the influenza virus, A*STAR researchers find.