A*STAR Bioinformatics Institute (A*STAR BII)

The AllerCatPro analysis workflow helps researchers predict the likelihood of a protein producing an allergic response in people.

The rate of discovery of human gene functions has fallen significantly

The 160K Natural Organism Library houses a wealth of novel compounds for biological research

Small fragments of the coagulating protein thrombin may reduce the likelihood of bacterial wound infection leading to sepsis

Mouse studies have revealed more about the mechanisms
behind cancer drugs in trials

A rotating fluorescent molecule that stays brighter in more viscous environments could shed light on the inner workings of the cellular environment

The long-held theory that Toll-like receptor 4 could be the link between obesity and inflammation is now being challenged

By taking advantage of the body’s
natural diversity, antibody drugs can be made less toxic by having a more localized
effect

Genetic switch activates transformation of stem cells into heart muscle cells

Tumor growth in a mouse model of lung cancer is
reduced using an RNA-based therapeutic that inhibits a metabolic pathway in tumor-initiating
cells

An image
processing algorithm designed to follow directional features shows promise for
mapping the blood vessel networks in the eye

Molecular simulations
reveal why certain cancer therapeutics may bind — or fail to bind — to mutant proteins