Cancer
Loading up a cure
10 May 2011A new type of polymer forms highly stable micelles with exceptional loading capacity for the targeted delivery of anticancer drugs
Hormonal attractions
15 Mar 2011Ultrasmall silicon wires could detect subtle changes in estrogen receptor-binding DNA sequences that are implicated in breast cancer
A very early warning
23 Nov 2010The human papillomavirus protein E2 may serve as a diagnostic marker for cervical intraepithelial neoplasia, the precursor stages of cervical cancer
Manipulating the milieu
23 Nov 2010Cancer cells secrete proteins that help them adapt to low-oxygen environments
Many a little makes a mickle
9 Nov 2010Genetic variations related to estrogen production have a cumulative effect on breast and endometrial cancer risk
Taking wraps off mammalian Rap1
9 Nov 2010Mammalian Rap1 controls transcription through the regulation of NF-κB activity
A double whammy
26 Oct 2010HPV18 puts women at a higher risk of developing cervical cancer because the virus converts a repressor of the cell cycle into an activator
On the trail of bacterial saboteurs
28 Sep 2010A previously unidentified bacterial protein variant gums up the gears of a last-resort cellular suicide mechanism
Finding the best approach in cancer research
31 Aug 2010Cancer geneticists in Singapore seek clinical relevance in large-scale cancer genomics studies
Directing the defenders and destroyers
17 Aug 2010Identification of a previously unknown interaction between immune-system cells points the way to novel cancer treatments
Thwarting a sneak attack
6 Jul 2010Metastatic spread begins surprisingly early in cancer but immune cells help keep it at bay
Fine-tuning cellular suicide
22 Jun 2010Increasing the efficacy and minimizing unwanted side effects of cancer gene therapy has been made possible using a new approach