Cancer

Ultrasmall silicon wires could detect subtle changes in estrogen receptor-binding DNA sequences that are implicated in breast cancer

The human papillomavirus protein E2 may serve as a diagnostic marker for cervical intraepithelial neoplasia, the precursor stages of cervical cancer

Cancer cells secrete proteins that help them adapt to low-oxygen environments

Genetic variations related to estrogen production have a cumulative effect on breast and endometrial cancer risk

Mammalian Rap1 controls transcription through the regulation of NF-κB activity

HPV18 puts women at a higher risk of developing cervical cancer because the virus converts a repressor of the cell cycle into an activator

A previously unidentified bacterial protein variant gums up the gears of a last-resort cellular suicide mechanism

Cancer geneticists in Singapore seek clinical relevance in large-scale cancer genomics studies

Identification of a previously unknown interaction between immune-system cells points the way to novel cancer treatments

Metastatic spread begins surprisingly early in cancer but immune cells help keep it at bay

Increasing the efficacy and minimizing unwanted side effects of cancer gene therapy has been made possible using a new approach

Analysis of the genome of a primitive seafloor dweller shows that a well-known system for controlling DNA damage is highly conserved evolutionarily