Genetics

A sophisticated algorithm combines expression data with information about patient outcomes to reveal cancer genes

Subtle sequence changes determine whether a common gene regulatory sequence acts as an ‘on’ or ‘off’ switch

A key signaling pathway in mammals forces cells in diverse tissues to ‘act their age’

A novel transcription factor can facilitate the reprogramming of somatic cells into stem cells

Embryonic stem cells keep their developmental options open with help from two recently identified genes

Construction of the world’s smallest controllable gear sets the stage for new nanoscale mechanical devices

A seemingly innocuous metabolic enzyme may play a key role in bringing about premature aging

A protein known for its role in antiviral defense works behind the scenes steering immune cell development and activity