Genetics

Large-scale analysis of Han Chinese populations reveals striking patterns of intriguing genetic diversity

A sophisticated algorithm combines expression data with information about patient outcomes to reveal cancer genes

Subtle sequence changes determine whether a common gene regulatory sequence acts as an ‘on’ or ‘off’ switch

A key signaling pathway in mammals forces cells in diverse tissues to ‘act their age’

Embryonic stem cells keep their developmental options open with help from two recently identified genes

A novel transcription factor can facilitate the reprogramming of somatic cells into stem cells

Construction of the world’s smallest controllable gear sets the stage for new nanoscale mechanical devices

A seemingly innocuous metabolic enzyme may play a key role in bringing about premature aging

A protein known for its role in antiviral defense works behind the scenes steering immune cell development and activity