A*STAR Genome Institute of Singapore (A*STAR GIS)
Mutations can tip a yin-yang balance
31 Mar 2015Investigating mutations of a crucial gene might assist treatment and prevention of asthma and other allergies
Teamwork uncovers genetic risk factors
3 Mar 2015Over 100 locations on the human genome associated with the risk of developing schizophrenia are identified in an international study
Genes of carcinogenic liver fluke revealed
17 Feb 2015The sequencing of a harmful Asian liver fluke’s genome brings hope of better treatments
Biodegrading by bacteria
20 Jan 2015Three bacterial strains capable of degrading a prolific toxic compound present in water and soils have been successfully isolated using gene sequencing
Genetic sleuth tracks undiagnosed diseases
16 Dec 2014A computer platform can pinpoint the genes behind rare diseases that have eluded diagnosis
Viral remnants are ‘facilitators’ not ‘fossils’
21 Oct 2014Once considered ‘junk’, certain virus-derived genomic elements have now been shown to actively regulate important developmental processes
‘False starts’ fuel cancer growth
9 Sep 2014A genomic survey reveals that abnormal initiation sites for gene expression may promote stomach cancer
Structure informs function
1 Jul 2014Genomic differences between individuals can change the physical organization of RNA transcripts, affecting their expression
A roadmap for pure organ cells
17 Jun 2014A new strategy minimizes the cellular contaminants that usually plague the differentiation of pluripotent stem cells
Helping cultured stem cells get back to nature
25 Mar 2014Cultured human embryonic stem cells given the ‘3iL’ treatment more closely resemble natural stem cells from the developing embryo
Understanding aggressive behavior
25 Feb 2014The discovery of a protein linked to the invasive spread of triple-negative breast cancer may lead to targeted therapies
Lone DNA link to lethal drug response
25 Feb 2014Doctors can now predict who will react badly to the leprosy drug dapsone, with Asian populations most at risk