A*STAR Genome Institute of Singapore (A*STAR GIS)

A genomic survey reveals that abnormal initiation sites for gene expression may promote stomach cancer

Genomic differences between individuals can change the physical organization of RNA transcripts, affecting their expression

A new strategy minimizes the cellular contaminants that usually plague the differentiation of pluripotent stem cells

Cultured human embryonic stem cells given the ‘3iL’ treatment more closely resemble natural stem cells from the developing embryo

The discovery of a protein linked to the invasive spread of triple-negative breast cancer may lead to targeted therapies

Doctors can now predict who will react badly to the leprosy drug dapsone, with Asian populations most at risk

A protein called SON ensures proper splicing of proteins to keep embryonic stem cells in a state of self-renewal

A molecular mechanism that directs both cell growth and death via one protein could underpin more efficient cancer therapies

Single-cell analysis shows how embryonic cells maintain proper patterns of gene regulation   

RNA and protein molecules join forces to switch on gene networks responsible for brain development

A computational approach reveals a myriad of protein pairs that combine to regulate gene activity

A decade after the opening of Biopolis, Singapore’s premier biomedical sciences research hub, A*STAR’s multifaceted activities are spurring discovery and innovation with a global reach