A*STAR Genome Institute of Singapore (A*STAR GIS)
Regulating stem cell behavior
28 Jan 2014A protein called SON ensures proper splicing of proteins to keep embryonic stem cells in a state of self-renewal
One protein, two important roles
28 Jan 2014A molecular mechanism that directs both cell growth and death via one protein could underpin more efficient cancer therapies
Preserving embryonic instructions
14 Jan 2014Single-cell analysis shows how embryonic cells maintain proper patterns of gene regulation
How a protein collaboration builds the brain
17 Dec 2013RNA and protein molecules join forces to switch on gene networks responsible for brain development
Biopolis: Ten years on
19 Nov 2013A decade after the opening of Biopolis, Singapore’s premier biomedical sciences research hub, A*STAR’s multifaceted activities are spurring discovery and innovation with a global reach
Picking out productive partnerships
19 Nov 2013A computational approach reveals a myriad of protein pairs that combine to regulate gene activity
Unlocking a secret of stem cell stability
5 Nov 2013Proper embryonic development depends on a signaling pathway that helps to preserve stem cell ‘immaturity’
Different regions, different genetic risk factors
5 Nov 2013A genetic study of Chinese patients reveals a prevalent risk factor for certain blood cancers not detected in European patients
Regulatory network revealed in embryonic stem cells
24 Sep 2013A location map for a signaling protein identifies key molecular targets in human embryonic stem cells
Lymphoma-linked risk factor identified
24 Sep 2013A specific genetic variant expressed in a key immune protein heightens an individual’s chance of developing follicular lymphoma
Analysis of sequence data falls into line
10 Sep 2013Formal mathematics underpins a new approach that standardizes the analysis of genome information
All sorted on a single microchip
13 Aug 2013A microchip that can identify human pathogens in a single test could revolutionize the diagnosis of infections