A*STAR Genome Institute of Singapore (A*STAR GIS)

The mysterious trigger of the NLRP1 inflammasome sensor has finally been identified: a protease found in the common cold-causing human rhinovirus tells our body that it has been invaded.

When combined with low doses of antibiotics, this biodegradable polymer can reduce or even reverse antimicrobial resistance.

Liver tumors gain immune tolerance by activating cellular mechanisms involved in fetal development.

For the first time, researchers have generated lab-grown livers that have functioning bile canaliculi, an important step towards modeling complex liver diseases.

A new sequencing technique called PORE-cupine combines artificial intelligence to reveal ribonucleic acid structures in cells.

A*STAR researchers have developed a new molecular imaging technique that enables the study of tissue physiology at ultra-high resolution.

A genetic cause for anencephaly, a common neural tube defect found in developing fetuses, has been identified for the first time.

Understanding the impact of antibiotics on both infants and adults could help restore the delicate balance of the gut microbiome.

Differences in the skin microbiome could reveal clues as to why some cases of atopic dermatitis are more severe than others.

Keystone bacterial species help to restore gut microbial diversity after treatment with antibiotics, paving the way for improved prebiotic and probiotic formulations.

A novel genomic biomarker may help to meet the demand for donor mesenchymal stem cells in regenerative medicine.

Being able to distinguish between different types of macrophages in the brain could shed light on inflammatory diseases such as Alzheimer’s.