Human Health and Potential (HHP)

Induced pluripotent stem cells have helped researchers map the role of the RFX6 gene in a rare congenital disorder known as Mitchell-Riley Syndrome.

A*STAR researchers have created the first machine learning model for predicting clinical outcomes of stem cell therapies in patients with cartilage disorders.

A newly-discovered role for an immune regulator in T cells may help unravel the molecular basis of inflammatory bowel disease and serve as a promising therapeutic target.

Asian patients with suspected but undiagnosed rare genetic diseases could get answers sooner thanks to next-generation sequencing technologies.

A newly-designed antimicrobial polymer offers a 2-in-1 solution to combat multidrug-resistant bacteria.

Data shows that antibodies produced as part of the COVID-19 immune response can neutralize a more transmissible variant of SARS-CoV-2.

Tracking how SARS-CoV-2 interacts with host cell receptors during infections may give us new ideas for COVID-19 drug targets.

Scientists identify a key molecular marker of muscle stem cells, providing novel insights into the mechanisms around muscle regeneration.

A novel 3D printing method developed by A*STAR researchers fabricates soft support for tissue growth, with embedded channels that ensure nutrient supply.

Some neutralizing antibodies against SARS-CoV-2 may heighten lung tissue damage from COVID-19, an A*STAR study finds.

Using a large-scale siRNA screen and CRISPR-Cas9 technology, researchers have pinpointed genes that can enhance antibody production in Chinese hamster ovary cells.

Precise and efficient C:G to G:C gene-editing enzymes could pave the way for new treatments for genetic diseases.