Immunology
Breakthrough infections from a memory lapse
22 Mar 2023Vaccinated people affected by COVID-19 variants have different memory B cell responses than their close contacts who remain healthy.
Making the most of natural cancer killers
30 Nov 2022A*STAR researchers discover a mechanism that fires up the metabolism of cancer-killing immune cells, paving the way for future cancer immunotherapies.
Mapping a missing link in malaria infection
20 May 2022A novel molecular mechanism by which a malarial parasite enters host cells may broaden possibilities in malaria vaccine development.
Speaking the same immune language
12 May 2022The first open-access database of mononuclear phagocytes, created by A*STAR researchers, provides insight into the biology of these immune cells and their roles in fighting disease.
Deciphering asthma’s genetic puzzle
14 Jan 2022A new link between gene variations in immune cells and allergic reactions explains why some individuals are more prone to developing asthma.
Tracing immune cells to their source
20 Dec 2021New research techniques are enabling scientists like SIgN’s Florent Ginhoux to unravel the complexities of the immune system like never before.
When allergies pass from mother to child
8 Dec 2021Maternal antibodies can cross the placenta and pass on mother’s allergies to her children in the womb.
Immune secrets of the symptom-free
26 Nov 2021Unique immune responses shield some COVID-19 patients from the disease’s worst effects.
Cracking the code of long COVID
5 Nov 2021Elevated levels of inflammatory factors may be linked to persistent COVID-19 symptoms, researchers find.
Flipping the switch on gut inflammation
26 Oct 2021A newly-discovered role for an immune regulator in T cells may help unravel the molecular basis of inflammatory bowel disease and serve as a promising therapeutic target.
Not all antibodies are created equal
10 Sep 2021Some neutralizing antibodies against SARS-CoV-2 may heighten lung tissue damage from COVID-19, an A*STAR study finds.
Memories of our first microbial encounters
8 Sep 2021Live bacterial strains present in fetal tissues may help lay the cornerstones of early and potentially life-long immunity.