Immunology

Disrupting the binding of a key protein pair in immune cells could help avert deadly allergic responses.

A deep dive into the skin barrier uncovers the critical role immune cells play in structural reinforcement and wound healing.

A groundbreaking multinational atlas of the body’s frontline defenders reveals hidden variations that could enhance precision health efforts worldwide.

A new spatial genomic scoring system outdoes existing tools at identifying patients at risk of recurring liver tumours.

A*STAR researchers discovered a potential new treatment for severe eczema by targeting a protein that regulates immune cell activity.

As the immune system ages, our susceptibility to conditions such as cancer increases, prompting researchers to develop advanced experimental models to study these pathways.

Neutrophils, typically our immune defenders, can paradoxically promote cancer progression when altered in tumours.

Researchers find that targeting nerve growth factor in melanomas transforms resistant ‘cold’ tumours into treatable ‘hot’ ones, adding new therapeutic options for challenging skin cancers.

An experimental antibody therapy for solid tumours in adults also shows promise in improving quality of life for paediatric patients.

While the new Omicron XBB COVID-19 subvariant deftly dodges immune defences even in vaccinated individuals, researchers find that mixed mRNA vaccines may offer a vital boost of protection.

Scientists survey how the mpox virus spreads through populations, the immunology of infections and current treatment interventions.

Inactivated COVID-19 vaccines could be an equally potent alternative for people with allergic sensitivities to mRNA-based vaccines.