A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)

Low levels of sugar entering into pancreatic cells may be the culprit behind insulin secretion defects in early-onset diabetes.

The mysterious trigger of the NLRP1 inflammasome sensor has finally been identified: a protease found in the common cold-causing human rhinovirus tells our body that it has been invaded.

Single-cell techniques have helped to identify a key molecular switch controlling how adult cells can be turned back to a stem cell-like state.

A*STAR researchers identify a novel mechanism in which an inflammatory protein heals wounds in healthy individuals but has the opposite effect in diabetics.

The mosquito-borne virus dodges immune clearance by cloaking itself in disarmed antibodies.

A new biomarker in liver tumor may help doctors predict how patients respond to immunotherapy.

New insights into the tumor microenvironment may help researchers stop the growth and spread of cancer to other parts of the body.

A genetic cause for anencephaly, a common neural tube defect found in developing fetuses, has been identified for the first time.

Researchers now have the tools to analyze the unique metabolic protein signatures of diverse immune cell subpopulations in different states of activation.

A novel genomic biomarker may help to meet the demand for donor mesenchymal stem cells in regenerative medicine.

The structure of collagen fibers may play a key role in the spread of breast cancer, with implications for clinical prognosis and treatment.

Flower-like ‘rosettes’ may help malaria parasites evade the body’s immune defences.