A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)

Asian patients with suspected but undiagnosed rare genetic diseases could get answers sooner thanks to next-generation sequencing technologies.

Scientists identify a key molecular marker of muscle stem cells, providing novel insights into the mechanisms around muscle regeneration.

A novel 3D printing method developed by A*STAR researchers fabricates soft support for tissue growth, with embedded channels that ensure nutrient supply.

A scalable cell culture platform can generate universal red blood cells from stem cells, paving the way for manufacturing an abundant supply of blood for transfusions.

In COVID-19 long-haulers, an unrelenting immune response damages blood vessels, making them more susceptible to developing blood clots.

Scientists have identified a network of neurons that drives overeating in response to environmental cues, rather than genuine hunger.

From expanding the genetic alphabet to uncovering antibiotics hidden in silent genes, A*STAR’s researchers are wielding the tools of synthetic biology to improve our lives in surprising ways.

Low levels of sugar entering into pancreatic cells may be the culprit behind insulin secretion defects in early-onset diabetes.

The mysterious trigger of the NLRP1 inflammasome sensor has finally been identified: a protease found in the common cold-causing human rhinovirus tells our body that it has been invaded.

Single-cell techniques have helped to identify a key molecular switch controlling how adult cells can be turned back to a stem cell-like state.

A*STAR researchers identify a novel mechanism in which an inflammatory protein heals wounds in healthy individuals but has the opposite effect in diabetics.

The mosquito-borne virus dodges immune clearance by cloaking itself in disarmed antibodies.