A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)
Keeping the beat of life
3 Nov 2021A protein in cilia called CFAP53 is responsible for the distinct beat patterns during embryonic development, researchers say.
A rare glimpse into the pancreas’ origins
1 Nov 2021Induced pluripotent stem cells have helped researchers map the role of the RFX6 gene in a rare congenital disorder known as Mitchell-Riley Syndrome.
Ending the diagnostic odyssey
20 Oct 2021Asian patients with suspected but undiagnosed rare genetic diseases could get answers sooner thanks to next-generation sequencing technologies.
Unboxing the muscle repair toolkit
20 Sep 2021Scientists identify a key molecular marker of muscle stem cells, providing novel insights into the mechanisms around muscle regeneration.
Bioprinting turns soft for tissue success
16 Sep 2021A novel 3D printing method developed by A*STAR researchers fabricates soft support for tissue growth, with embedded channels that ensure nutrient supply.
Scaling up universal blood production
25 Aug 2021A scalable cell culture platform can generate universal red blood cells from stem cells, paving the way for manufacturing an abundant supply of blood for transfusions.
Catching the clot culprit in COVID-19
17 Aug 2021In COVID-19 long-haulers, an unrelenting immune response damages blood vessels, making them more susceptible to developing blood clots.
The brain circuit that encourages overeating
2 Aug 2021Scientists have identified a network of neurons that drives overeating in response to environmental cues, rather than genuine hunger.
Advancing synthetic biology across all fronts
16 Jul 2021From expanding the genetic alphabet to uncovering antibiotics hidden in silent genes, A*STAR’s researchers are wielding the tools of synthetic biology to improve our lives in surprising ways.
Opening the cellular gates to glucose
2 Jul 2021Low levels of sugar entering into pancreatic cells may be the culprit behind insulin secretion defects in early-onset diabetes.
NLRP1: How the body senses the common cold virus
28 Jun 2021The mysterious trigger of the NLRP1 inflammasome sensor has finally been identified: a protease found in the common cold-causing human rhinovirus tells our body that it has been invaded.
Sifting out rare stem cells
14 Jun 2021Single-cell techniques have helped to identify a key molecular switch controlling how adult cells can be turned back to a stem cell-like state.