A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)
Call for rigor over COVID-19 exosome therapy
22 Jul 2020Stem cell experts recognize the potential of exosomes for treating COVID-19 pneumonia, but caution that rigorous clinical testing is needed.
Unlocking the full potential of stem cells
20 Apr 2020Modifying how embryonic stem cells use sugar can switch them into a totipotent state, A*STAR researchers say.
Defying convention in cancer drug discovery
2 Apr 2020Just because a molecular target resides inside a cancer cell does not mean that it cannot be targeted by antibodies, says Qi Zeng, founder of A*STAR spin-off company Intra-ImmuSG.
Finding the missing link for a rare heritable disease
22 Jan 2020Mutations accelerating the degradation of the protein gelsolin are responsible for amyloid plaque buildup in patients suffering from familial amyloidosis, Finnish type.
How bacteria move their DNA around
22 Jan 2020A*STAR researchers have figured out the detailed structure of a type of protein filament responsible for tethering and moving DNA in bacteria cells.
Sounding the alarm when things are fishy
31 Dec 2019A*STAR researchers uncover how bacteria and the immune system generate alarm behavior in fish.
Protein-protein interactions made visible
20 Dec 2019A*STAR researchers have turned a bacterial protein into a biosensor that can be used to visualize interactions between proteins.
Enhancing the immune response to fungal infections
20 Dec 2019A*STAR scientists have found a way to boost the activity of neutrophils, a subset of immune cells, against disease-causing fungi.
Weaponizing stem cells in the war on diabetes
11 Dec 2019From replacing the insulin producing cells of the body, to serving as genetic and drug screening platforms, stem cells could change the landscape of available treatments for diabetes.
How to maim a virus without killing it
7 Nov 2019Targeted mutagenesis is being used to create live-attenuated vaccines against the chikungunya virus.
The P value is dead, long live the estimation plot
25 Oct 2019Estimation plots provide researchers with a more complete picture of the significance of their results than traditional P values, say A*STAR scientists.
Out for blood in the fight against cancer
30 Sep 2019By interfering with the production and downstream activity of a molecule called Agrin in tumors, scientists can stop the sprouting of blood vessels that promote cancer progression.