A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)
Sounding the alarm when things are fishy
31 Dec 2019A*STAR researchers uncover how bacteria and the immune system generate alarm behavior in fish.
Protein-protein interactions made visible
20 Dec 2019A*STAR researchers have turned a bacterial protein into a biosensor that can be used to visualize interactions between proteins.
Enhancing the immune response to fungal infections
20 Dec 2019A*STAR scientists have found a way to boost the activity of neutrophils, a subset of immune cells, against disease-causing fungi.
Weaponizing stem cells in the war on diabetes
11 Dec 2019From replacing the insulin producing cells of the body, to serving as genetic and drug screening platforms, stem cells could change the landscape of available treatments for diabetes.
How to maim a virus without killing it
7 Nov 2019Targeted mutagenesis is being used to create live-attenuated vaccines against the chikungunya virus.
The P value is dead, long live the estimation plot
25 Oct 2019Estimation plots provide researchers with a more complete picture of the significance of their results than traditional P values, say A*STAR scientists.
Out for blood in the fight against cancer
30 Sep 2019By interfering with the production and downstream activity of a molecule called Agrin in tumors, scientists can stop the sprouting of blood vessels that promote cancer progression.
A vision for better eye treatments
23 Aug 2019Researchers at A*STAR have invented a biodegradable thermogel that mimics the clear, gelatinous substance called vitreous in the eye.
Getting to the roots of early-onset diabetes
23 Aug 2019Mutations in the gene HNF4A impair liver and pancreas development, indicating that maturity-onset diabetes of the young starts much earlier than initially thought.
A leg up for neuroscience
13 Aug 2019An automated machine learning system for analyzing leg movements in fruit flies is helping A*STAR researchers shed light on how neurodegenerative diseases develop.
Targeting cancer from the inside out
13 Aug 2019In times of stress, cancer cells move a protein normally found inside the cell to the cell surface, making it accessible to antibodies for immunotherapy.
Crippling cancer cell growth
29 Jul 2019Disruption of the methionine cycle in tumor-initiating cells disarms their tumorigenic capabilities, researchers say.