A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)
A vision for better eye treatments
23 Aug 2019Researchers at A*STAR have invented a biodegradable thermogel that mimics the clear, gelatinous substance called vitreous in the eye.
Getting to the roots of early-onset diabetes
23 Aug 2019Mutations in the gene HNF4A impair liver and pancreas development, indicating that maturity-onset diabetes of the young starts much earlier than initially thought.
A leg up for neuroscience
13 Aug 2019An automated machine learning system for analyzing leg movements in fruit flies is helping A*STAR researchers shed light on how neurodegenerative diseases develop.
Targeting cancer from the inside out
13 Aug 2019In times of stress, cancer cells move a protein normally found inside the cell to the cell surface, making it accessible to antibodies for immunotherapy.
Crippling cancer cell growth
29 Jul 2019Disruption of the methionine cycle in tumor-initiating cells disarms their tumorigenic capabilities, researchers say.
One test to determine them all
14 Jun 2019A*STAR researchers have devised a method that can detect and distinguish closely related flaviviruses with 100 percent accuracy.
A one-shot assay for flavivirus identification
14 Jun 2019Proteomics expert Ruedi Aebersold discusses the use of multiplex targeted mass spectrometry for one-shot flavivirus diagnosis.
A RIPple effect during infection
14 Jun 2019Researchers have obtained a high-resolution structure of the RIP2 protein complex and detailed its interactions with other immune proteins.
Clearing the air on cilia development
24 May 2019A*STAR researchers have uncovered the sequence of genetic events behind the development of motile cilia in airways.
How cancer cells tip the Bim balance in their favor
24 May 2019Cancer cells evade Taxol-induced cell death by downregulating the expression of a protein known as BimEL.
Getting mature human heart muscle cells to multiply again
24 May 2019By triggering the Wnt signaling pathway, A*STAR scientists were able to reactivate proliferation in mature human heart muscle cells.
How bacteria influence host immunity
24 May 2019When parts of a bacteria’s cell wall enter into circulation, its host experiences more severe autoimmune reactions.