A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)

By using nanosized charged polymer balls to attack tumors directly rather than carry drugs, researchers have found a way to overcome drug resistance

Similarities between the two gap phases of the
cell cycle indicate a default biochemical program in living cells

Rings of filamentous protein zip together to seal the embryo, creating watertight junctions between adjacent cells

Deep data analytics drive the development of a technique
that sheds light on drug action by monitoring the dynamics of thousands of protein complexes simultaneously
within intact cells

Relocation
of enzymes involved in protein modification makes it easier for cancer to
spread

Tumor growth in a mouse model of lung cancer is
reduced using an RNA-based therapeutic that inhibits a metabolic pathway in tumor-initiating
cells

Assay
for genetic quirk can provide a wealth of
information on patient disease status and prognosis

Microtubule bridges organize the cytoskeletons of cells in the early embryo

To avoid getting sidetracked by distractions, neurons in the brain’s short-term
memory center reorganize their activity patterns

The
effect of gut bacteria on specific immune cells is behind persistent liver
inflammation in chronic viral hepatitis

Two proteins maintain embryonic stem cell pluripotency
through different means

A rare mutation causes severe growth retardation and spine malformation in humans and mice