A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)

With
an eye to transfusion for patients, researchers are getting close to growing huge
numbers of red blood cells in industrial-grade vats

Mouse studies have revealed more about the mechanisms
behind cancer drugs in trials

A dual-function protein switch can be tweaked to improve the effectiveness of cellular reprogramming

Revealing how a gene is activated in cancer cells to produce an enzyme that helps the cells thrive could lead to new treatments

A high-throughput screening technique detects special messenger RNA molecules that sense and respond to environmental signals

By using nanosized charged polymer balls to attack tumors directly rather than carry drugs, researchers have found a way to overcome drug resistance

Similarities between the two gap phases of the
cell cycle indicate a default biochemical program in living cells

Rings of filamentous protein zip together to seal the embryo, creating watertight junctions between adjacent cells

Deep data analytics drive the development of a technique
that sheds light on drug action by monitoring the dynamics of thousands of protein complexes simultaneously
within intact cells

Relocation
of enzymes involved in protein modification makes it easier for cancer to
spread

Tumor growth in a mouse model of lung cancer is
reduced using an RNA-based therapeutic that inhibits a metabolic pathway in tumor-initiating
cells

Assay
for genetic quirk can provide a wealth of
information on patient disease status and prognosis