Institute of Molecular and Cell Biology (IMCB)

Signals that pass between genetically abnormal epithelial cells and their genetically normal support cells drive tumor formation in a fruit fly cancer model

The DNA of stem cells that mature into sperm stands ready to express factors required for reproduction and early development

Humans may have benefited from mobile genetic element insertions

A genetic screen in zebrafish identifies genes implicated in the development of cell structures linked to respiratory disease in humans

Regulatory mechanisms that help ‘trap’ an enzyme may prevent the production of cancer-promoting molecules

A zebrafish-based screening method reveals compounds that could help contain the effects of immunological disorders

Newly identified hormone ELABELA regulates the generation of the embryo’s endoderm and is required for the normal formation of the heart

An enzyme that silences DNA activity may be crucially involved in health and cancer

Improved understanding of the proteins that help the body to control appetite may be useful for the treatment of obesity

Whole-genome sequencing of the elephant shark offers insights into bone disease and immunity in humans

Gene expression profiling reveals the mechanisms that guide the fate of individual embryonic cells

The lamprey genome reveals new insights into the history of vertebrate evolution