A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)

A protein on which two molecular pathways converge could be the key to new cancer therapies

Uncovering the role of a particular protein in the progression of ovarian cancer may assist both prognosis and targeted treatment

Smooth muscle cells designed to mimic blood vessels in the brain may help to understand Alzheimer’s

Signals that pass between genetically abnormal epithelial cells and their genetically normal support cells drive tumor formation in a fruit fly cancer model

The DNA of stem cells that mature into sperm stands ready to express factors required for reproduction and early development

Humans may have benefited from mobile genetic element insertions

Regulatory mechanisms that help ‘trap’ an enzyme may prevent the production of cancer-promoting molecules

A genetic screen in zebrafish identifies genes implicated in the development of cell structures linked to respiratory disease in humans

A zebrafish-based screening method reveals compounds that could help contain the effects of immunological disorders

Newly identified hormone ELABELA regulates the generation of the embryo’s endoderm and is required for the normal formation of the heart

An enzyme that silences DNA activity may be crucially involved in health and cancer

Improved understanding of the proteins that help the body to control appetite may be useful for the treatment of obesity