A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)

Newly identified hormone ELABELA regulates the generation of the embryo’s endoderm and is required for the normal formation of the heart

An enzyme that silences DNA activity may be crucially involved in health and cancer

Improved understanding of the proteins that help the body to control appetite may be useful for the treatment of obesity

Whole-genome sequencing of the elephant shark offers insights into bone disease and immunity in humans

Gene expression profiling reveals the mechanisms that guide the fate of individual embryonic cells

A protein known as seipin regulates fat development through cytoskeleton remodeling

The lamprey genome reveals new insights into the history of vertebrate evolution

Disruptions in a protein-processing pathway appear to promote aggressive proliferation and invasion in tumor cells

Single-cell analysis shows how embryonic cells maintain proper patterns of gene regulation   

A newly discovered early-warning system triggers cellular suicide when a critical RNA editing system breaks down

A decade after the opening of Biopolis, Singapore’s premier biomedical sciences research hub, A*STAR’s multifaceted activities are spurring discovery and innovation with a global reach

Researchers in Singapore discover a molecule that regulates production of the pheromones that determine whether male flies attract males or females