A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)
Tightening the belt on tumor growth
24 May 2011A newly identified molecular mechanism could lead to treatments to control cancer
The key to transformation
10 May 2011The regulatory protein Wbp2 enhances the ability of the transcriptional co-activator TAZ to transform healthy cells into cancer cells
A matter of balance
26 Apr 2011A zebrafish study reveals how progenitor cells respond to multiple signals during embryonic development
Separate ways
29 Mar 2011Two guidance receptors steer the collective migration of border cells in different ways
Keeping up with the neighbors
15 Feb 2011Protein structures reveal details of how some bacteria stay in touch with their community
Lend me your ears
15 Feb 2011A zebrafish study provides new insights into factors that influence the formation of functionally important ear stones
Go or no-go?
1 Feb 2011The crystal structure of the Dom34–Hbs1 complex reveals how cells recognize and remove defective messenger RNA with stalled elongation through ‘no-go’ decay
A new player in protein secretion
9 Nov 2010Scientists are establishing the basic molecular network of a new player involved in protein secretion and clarifying its regulation in mammalian cells
Taking wraps off mammalian Rap1
9 Nov 2010Mammalian Rap1 controls transcription through the regulation of NF-κB activity
On the trail of bacterial saboteurs
28 Sep 2010A previously unidentified bacterial protein variant gums up the gears of a last-resort cellular suicide mechanism
Regulatory dysfunction spells trouble
28 Sep 2010Discovery of the mechanism regulating the expression of an enzyme implicated in human cancer could open new avenues for treatment
A pause that refreshes
14 Sep 2010Pre-treatment with a cell division-blocking drug protects healthy cells from the devastating effects of chemotherapy