A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)

On the back of growing drug resistance, researchers at the A*STAR Institute of Molecular and Cell Biology are exploring new targets to develop effective antibacterial compounds

Cellular trafficking modulates levels of a brain protein associated with a variety of neurological disorders

A newly identified molecular mechanism could lead to treatments to control cancer

The regulatory protein Wbp2 enhances the ability of the transcriptional co-activator TAZ to transform healthy cells into cancer cells

A zebrafish study reveals how progenitor cells respond to multiple signals during embryonic development

Two guidance receptors steer the collective migration of border cells in different ways

Protein structures reveal details of how some bacteria stay in touch with their community

A zebrafish study provides new insights into factors that influence the formation of functionally important ear stones

The crystal structure of the Dom34–Hbs1 complex reveals how cells recognize and remove defective messenger RNA with stalled elongation through ‘no-go’ decay

Scientists are establishing the basic molecular network of a new player involved in protein secretion and clarifying its regulation in mammalian cells

Mammalian Rap1 controls transcription through the regulation of NF-κB activity

Discovery of the mechanism regulating the expression of an enzyme implicated in human cancer could open new avenues for treatment