A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)

Mammalian Rap1 controls transcription through the regulation of NF-κB activity

A previously unidentified bacterial protein variant gums up the gears of a last-resort cellular suicide mechanism

Discovery of the mechanism regulating the expression of an enzyme implicated in human cancer could open new avenues for treatment

Pre-treatment with a cell division-blocking drug protects healthy cells from the devastating effects of chemotherapy

Mutations in a structural protein sabotage signaling pathways that control skin cell survival

An analysis of capping protein interactions provides insight into how cells move

Disrupted cellular transport of sugar-coating enzymes may cause cancers to spread

The interaction points between proteins regulating cell growth could offer promising future targets for fighting cancer

The proteins that provide essential infrastructure for bacteria exhibit remarkable diversity of structure and function

A protein primarily active in the nucleus also operates within the cytoplasm to orchestrate cell movement

Cytoskeletal proteins stabilize a factor that helps cells to refine their sense of direction

A previously uncharacterized cellular transport mechanism controls activity of a receptor involved in various cancers