A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)

The National Research Foundation Singapore will support the research ambition of four A*STAR researchers through two key programmes—the NRF Fellowship and the NRF Investigatorship.

A molecular tagging tool developed in Singapore identifies novel protein interactions on the surface of cancer cells.

A breakthrough discovery describes key molecular players involved in insulin secretion, paving the way for a new class of gene therapies targeting type 2 diabetes.

Using improved mouse models for gastric cancer, A*STAR scientists uncover a pool of cancer stem cells key to disease progression.

Ushering in an era of targeted precision medicine, scientists across A*STAR are propelling the research, commercialisation and implementation of RNA-based therapeutics.

Delving deep into the fundamentals of development and the frontiers of disease therapeutics, Mei Sheng Lau unravels the roles chromatin plays in gene regulation.

A*STAR researchers challenge existing theories around intestinal stem cell biology using a newly developed animal model of intestinal regeneration.

New data suggest that metformin administered to pregnant mothers may have unintended effects on the fetus, prompting the need for further assessment of the drug’s risk-benefit ratio.

Metabolic changes in the neurons of patients with amyotrophic lateral sclerosis may be reversed with vitamin B3 supplements.

A breakthrough stem cell transplant technology uses donated cadaver eyes to restore vision in patients with retinal degeneration.

From the public sector to innovative startups and industry giants, A*STAR scholars are blazing the trail across Singapore’s research ecosystem.

Researchers engineer specialized T cells that can transiently and effectively attack liver cancer cells even in the presence of immunosuppressive drugs.