Proteins

Clarifying how deadly protein toxins hijack cellular processes to enter human cells will help in the development of antidotes

Time-lapse imaging reveals how cells get a feel for their environment

Structural analysis of the interaction between human leukocyte antigens and hepatitis B viruses reveals a path to better vaccine design

Small molecules that bind one protein inside the test tube may or may not bind the same protein inside the living cell

The regulatory protein Wbp2 enhances the ability of the transcriptional co-activator TAZ to transform healthy cells into cancer cells

Efforts to understand a signaling factor’s contradictory behavior reveal a master switch for organ development

Three proteins work together to induce the production of an inflammatory factor in human immune cells

Chinese hamster ovary and baby hamster kidney cell lines are the best choices for producing therapeutic glycoprotein that stays in the bloodstream longer

Scientists are establishing the basic molecular network of a new player involved in protein secretion and clarifying its regulation in mammalian cells

Mammalian Rap1 controls transcription through the regulation of NF-κB activity

A highly truncated receptor protein variant retains the ability to modulate metabolic activity in mice

Molecular dynamics simulations show why scientists have failed to generate an active form of the protein kinase PAK1