Proteins

Molecular dynamics simulations show why scientists have failed to generate an active form of the protein kinase PAK1

A molecular library yields a promising candidate for thwarting the ability of cancer cells to elude chemotherapy

The proteins that provide essential infrastructure for bacteria exhibit remarkable diversity of structure and function

Dividing cells employ multiple, parallel countermeasures to prevent the transmission of damaged genetic material

Two calcium-binding events set major structural rearrangements into motion for an important regulatory protein of human cells