Singapore Immunology Network (SIgN)

A genome-wide association study identifies six new susceptibility loci tied to the age-old disease of leprosy

Monocytes and macrophages may promote human cancer growth

A new technique dramatically enhances profiling and classification of cells involved in innate immunity

A cell surface protein known to regulate innate immune responses also affects the adaptive immune system

Investigating mutations of a crucial gene might assist treatment and prevention of asthma and other allergies

Proof that CD14⁺ immune cells in the skin are derived from monocytes in the blood helps understand their function in regulating immunity

Insights into a signaling network inside blood-forming cells could lead to refinements in immunosuppressive therapy

Detailed molecular analysis shows extremely limited diversity among one group of immune cells and uncovers a new population

Modulating the expression of a protein that protects against viral infection allows researchers to study dengue vaccines in mice

Malaria-infected cells may latch onto healthy blood cells for protection rather than to aid transmission

An antibody that blocks immune signaling offers a promising research tool and potential therapeutic agent

Details of monkey antibodies against chikungunya virus could help to fight the disease in humans