A*STAR Singapore Immunology Network (A*STAR SIgN)

Success in deciphering the mechanisms of infection and spread of Chikungunya virus within humans points the way to control strategies

Metastatic spread begins surprisingly early in cancer but immune cells help keep it at bay

Genomic technologies developed by A*STAR’s Singapore Immunology Network (SIgN) form the basis for a new vaccine development platform that could pave the way for cost-effective personalized therapy

Immune cells infected by the dengue virus play a key role in fighting against viral growth

A ‘whole parasite’ strategy could lead to a vaccine for one of the world’s deadliest diseases

Drugs that selectively target pre-symptomatic, liver-stage malarial infection could ultimately help thwart this deadly disease.

Subtle sequence changes determine whether a common gene regulatory sequence acts as an ‘on’ or ‘off’ switch

Surface features enable efficient purification of cells that help thwart autoimmunity and prevent tissue graft rejection

Immune cells that target tumors can be boosted in chronic hepatitis B sufferers

A protein known for its role in antiviral defense works behind the scenes steering immune cell development and activity