A*STAR Singapore Immunology Network (A*STAR SIgN)

Details of monkey antibodies against chikungunya virus could help to fight the disease in humans

Crystal structure reveals how minor variations make receptor proteins activate or inhibit natural killer cells

House dust mites may be the primary trigger for allergy-associated respiratory problems in tropical urban environments such as Singapore

A panel of p53 variants helps scientists confidently identify genes controlled by the master regulator protein

Understanding the diversity of immature red blood cells in greater detail could help protect against Asia’s most common form of malaria

Disease-causing IgE antibodies are kept under wraps to avoid allergic responses

A more efficient production process for influenza vaccines could help to cope with future pandemics

Uncovering the molecular mechanisms behind immune system activation could help in future gene therapies

Manipulating a population of blood cells in an individual could help to activate immune responses against the hepatitis B virus

A method that stops the dengue virus from resembling a host’s RNA could yield an effective and affordable vaccine

Understanding how the drug plerixafor mobilizes a specific type of white blood cell bodes well for improving treatment regimens

Brain-damaging complications of malaria arise from the immune response to parasite antigens absorbed by blood vessels