A*STAR Singapore Immunology Network (A*STAR SIgN)

T cells use a multi-pronged approach to promote an inflammatory counterattack against infectious threats

Vaccine development could be aided by increased understanding of the physical interactions between immune cells

The mechanism by which malaria parasites accumulate in the brain and other deep tissues of model mice has been identified

Structural analysis of the interaction between human leukocyte antigens and hepatitis B viruses reveals a path to better vaccine design

The antifolate drug methotrexate is highly potent against the malaria parasite Plasmodium vivax

Patients with chikungunya fever experience persistent joint pain because their body produces high amounts of pro-inflammatory cytokines

Three proteins work together to induce the production of an inflammatory factor in human immune cells

Antibodies derived from an individual who had previously been exposed to the Chikungunya virus raise hope of a new therapy

A subset of human immune cells monitors blood vessels for viral infection

A device that runs on batteries and fits in the palm of your hand can detect viruses in just 35 minutes

Identification of a previously unknown interaction between immune-system cells points the way to novel cancer treatments

The Singapore Immunology Network has launched a US$2 million program to identify biomarkers for this ancient infectious disease