A*STAR Singapore Immunology Network (A*STAR SIgN)

By tapping into the inner workings of cells, Jinmiao Chen uses novel analytical technologies to understand why immune responses vary greatly among individuals.

A*STAR researchers identified immune markers that can distinguish between common febrile diseases in Saudi Arabia.

Controlling the delicate balance between immune cells called granulocytes and monocytes could make the difference between a healthy immune response and life-threatening sepsis.

Liver tumors gain immune tolerance by activating cellular mechanisms involved in fetal development.

The mosquito-borne virus dodges immune clearance by cloaking itself in disarmed antibodies.

A new biomarker in liver tumor may help doctors predict how patients respond to immunotherapy.

The discovery of how aging impacts memory T cells may unlock novel therapeutic targets to boost immune protection in older adults.

These novel immune signatures identify patients most at risk for developing severe COVID-19 symptoms.

Using flow cytometry, researchers have developed a sensitive and specific test for COVID-19 that can identify asymptomatic carriers.

Differences in the skin microbiome could reveal clues as to why some cases of atopic dermatitis are more severe than others.

Being able to distinguish between different types of macrophages in the brain could shed light on inflammatory diseases such as Alzheimer’s.

The structure of collagen fibers may play a key role in the spread of breast cancer, with implications for clinical prognosis and treatment.