A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)

Whether combating global viral threats or advancing next-generation telecommunications, the A*STAR winners of the 2025 President’s Science and Technology Awards showcase the talent and drive at the foundations of world-class research excellence.

At the core of A*STAR’s research mission, Kian Teik Beh underscores the importance of prioritising real-world needs and bridging discovery with deployment in the clinic, industry and marketplace.

An integrated sequencing platform successfully uncovers a hidden genomic variant of a rare liver disease, sparking new precision medicine options.

Originally aimed at tumours, a new antibody treatment also offers a safer alternative to eye injections for neovascular eye diseases.

Clinical trial results show a new antibody drug with an unconventional approach extends survival for patients with various aggressive cancers.

A new chemical testing platform harnesses colour- and light-producing genes from wildlife to speed the search for promising RNA-based therapeutics.

Targeting a key gene can help prevent the body’s immune fighters from wearing out when attacking tumour cells, offering a new treatment strategy against cancer.

The distance between certain cell types in pancreatic tumours can predict whether patients live longer.

SINGA scholar Senuri De Silva merges computational biology with translational science to unlock protein-level insights into the mechanisms of disease.

Integrating molecular insights from several omics profiling approaches, A*STAR research initiatives are deepening our understanding of human physiology and unearthing new diagnostic and therapeutic opportunities.

Scientists dig into tempeh to uncover how microbial action breaks down soybean proteins into smaller, more digestible and more nutritious forms.

This year, the National Research Foundation Singapore is empowering three A*STAR researchers to push the boundaries of science.