A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)

Comparing hypothalamic networks in zebrafish and mice reveals evolutionarily conserved neuronal pathways that regulate appetite across vertebrates.

A*STAR researchers take a layered approach to create fibrous alternative meat products that mimic the sensory profiles of the real deal.

Disrupting the binding of a key protein pair in immune cells could help avert deadly allergic responses.

Self-looping molecules could be the key to unlocking the potential of RNA-based vaccines and therapies.

Whether combating global viral threats or advancing next-generation telecommunications, the A*STAR winners of the 2025 President’s Science and Technology Awards showcase the talent and drive at the foundations of world-class research excellence.

At the core of A*STAR’s research mission, Kian Teik Beh underscores the importance of prioritising real-world needs and bridging discovery with deployment in the clinic, industry and marketplace.

An integrated sequencing platform successfully uncovers a hidden genomic variant of a rare liver disease, sparking new precision medicine options.

Originally aimed at tumours, a new antibody treatment also offers a safer alternative to eye injections for neovascular eye diseases.

Clinical trial results show a new antibody drug with an unconventional approach extends survival for patients with various aggressive cancers.

A new chemical testing platform harnesses colour- and light-producing genes from wildlife to speed the search for promising RNA-based therapeutics.

Targeting a key gene can help prevent the body’s immune fighters from wearing out when attacking tumour cells, offering a new treatment strategy against cancer.

The distance between certain cell types in pancreatic tumours can predict whether patients live longer.