Institute of Molecular and Cell Biology (IMCB)

A T cell therapy innovation may offer new hope for acute myeloid leukemia patients who relapse after conventional treatment.

A new polymer gel may offer a drug-free solution to preventing retinal scarring after eye surgery.

Scientists discover a potential therapeutic target to tackle a dangerous drug-resistant yeast strain.

A protein called Agrin naturally produced in the skin could soon be the active ingredient in a treatment to boost skin repair in non-healing wounds.

Multidisciplinary efforts across A*STAR are paving the way toward Singapore’s precision medicine vision.

New gastric cancer insights come to light with the help of powerful single-cell technologies.

A molecular tagging tool developed in Singapore identifies novel protein interactions on the surface of cancer cells.

A breakthrough discovery describes key molecular players involved in insulin secretion, paving the way for a new class of gene therapies targeting type 2 diabetes.

Using improved mouse models for gastric cancer, A*STAR scientists uncover a pool of cancer stem cells key to disease progression.

A*STAR researchers challenge existing theories around intestinal stem cell biology using a newly developed animal model of intestinal regeneration.

New data suggest that metformin administered to pregnant mothers may have unintended effects on the fetus, prompting the need for further assessment of the drug’s risk-benefit ratio.

Metabolic changes in the neurons of patients with amyotrophic lateral sclerosis may be reversed with vitamin B3 supplements.