A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)
Clearing the air on cilia development
24 May 2019A*STAR researchers have uncovered the sequence of genetic events behind the development of motile cilia in airways.
How cancer cells tip the Bim balance in their favor
24 May 2019Cancer cells evade Taxol-induced cell death by downregulating the expression of a protein known as BimEL.
Getting mature human heart muscle cells to multiply again
24 May 2019By triggering the Wnt signaling pathway, A*STAR scientists were able to reactivate proliferation in mature human heart muscle cells.
How bacteria influence host immunity
24 May 2019When parts of a bacteria’s cell wall enter into circulation, its host experiences more severe autoimmune reactions.
Growing a ‘spine’ on a chip
24 May 2019Microfluidic device allows for precise control of growth factor gradients, mimicking natural spinal cord development in vitro.
Fly screen captures behavioral effects of venom
2 Apr 2019Injecting flies with snail venom could help us discover molecules for developing new drugs
Tapeworm drug targets common vulnerability in tumor cells
17 Mar 2019Drug screen reveals safe, potent, broad-spectrum anticancer compound
Spinal organoids mimic neurodegenerative disease
17 Mar 2019New spinal-cord-like cell clusters could be used to study and find treatments for nerve cell degeneration
Reprogramming T cells to attack solid tumors
17 Mar 2019A two-pronged genetic manipulation of T cells of the human immune system could lead to more effective cancer treatments
Metabolic remodeling during regeneration
5 Mar 2019Insights into the molecular changes in regenerating liver cells may reveal ways to help patients recover from surgery or disease
From suspected instigator to unlikely hero
3 Feb 2019A*STAR researchers have revealed the mechanism behind the way receptor TLR-9 protects against lupus
Gut feelings are not for everyone
14 Jan 2019Gut bacteria in fruit flies do not have a major influence on behavior