A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)
Growing a ‘spine’ on a chip
24 May 2019Microfluidic device allows for precise control of growth factor gradients, mimicking natural spinal cord development in vitro.
Fly screen captures behavioral effects of venom
2 Apr 2019Injecting flies with snail venom could help us discover molecules for developing new drugs
Spinal organoids mimic neurodegenerative disease
17 Mar 2019New spinal-cord-like cell clusters could be used to study and find treatments for nerve cell degeneration
Reprogramming T cells to attack solid tumors
17 Mar 2019A two-pronged genetic manipulation of T cells of the human immune system could lead to more effective cancer treatments
Tapeworm drug targets common vulnerability in tumor cells
17 Mar 2019Drug screen reveals safe, potent, broad-spectrum anticancer compound
Metabolic remodeling during regeneration
5 Mar 2019Insights into the molecular changes in regenerating liver cells may reveal ways to help patients recover from surgery or disease
From suspected instigator to unlikely hero
3 Feb 2019A*STAR researchers have revealed the mechanism behind the way receptor TLR-9 protects against lupus
Gut feelings are not for everyone
14 Jan 2019Gut bacteria in fruit flies do not have a major influence on behavior
Biology of our ancient ancestor takes shape
14 Jan 2019Primitive microbes have cytoskeletal proteins that are structurally and functionally similar to those found in humans
Uncapping a new therapy
19 Dec 2018A deeper understanding of chromosome capping could improve therapies for both cancer and aging
Getting a grip on hand, foot and mouth disease
19 Dec 2018Testing for human microRNA in saliva could help prevent outbreaks of hand, foot and mouth disease in children
Identifying white knights of the arteries
29 Nov 2018A sub-group of white blood cells help maintain arterial structure and may aid development of treatments for vascular diseases