A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)
Crippling cancer cell growth
29 Jul 2019Disruption of the methionine cycle in tumor-initiating cells disarms their tumorigenic capabilities, researchers say.
One test to determine them all
14 Jun 2019A*STAR researchers have devised a method that can detect and distinguish closely related flaviviruses with 100 percent accuracy.
A one-shot assay for flavivirus identification
14 Jun 2019Proteomics expert Ruedi Aebersold discusses the use of multiplex targeted mass spectrometry for one-shot flavivirus diagnosis.
A RIPple effect during infection
14 Jun 2019Researchers have obtained a high-resolution structure of the RIP2 protein complex and detailed its interactions with other immune proteins.
Clearing the air on cilia development
24 May 2019A*STAR researchers have uncovered the sequence of genetic events behind the development of motile cilia in airways.
How cancer cells tip the Bim balance in their favor
24 May 2019Cancer cells evade Taxol-induced cell death by downregulating the expression of a protein known as BimEL.
Getting mature human heart muscle cells to multiply again
24 May 2019By triggering the Wnt signaling pathway, A*STAR scientists were able to reactivate proliferation in mature human heart muscle cells.
How bacteria influence host immunity
24 May 2019When parts of a bacteria’s cell wall enter into circulation, its host experiences more severe autoimmune reactions.
Growing a ‘spine’ on a chip
24 May 2019Microfluidic device allows for precise control of growth factor gradients, mimicking natural spinal cord development in vitro.
Fly screen captures behavioral effects of venom
2 Apr 2019Injecting flies with snail venom could help us discover molecules for developing new drugs
Tapeworm drug targets common vulnerability in tumor cells
17 Mar 2019Drug screen reveals safe, potent, broad-spectrum anticancer compound
Spinal organoids mimic neurodegenerative disease
17 Mar 2019New spinal-cord-like cell clusters could be used to study and find treatments for nerve cell degeneration