Highlights
Immunology
A RIPple effect during infection
14 June 2019Researchers have obtained a high-resolution structure of the RIP2 protein complex and detailed its interactions with other immune proteins.
Mechanical Engineering
Sound barriers inspired by origami
14 June 2019A*STAR scientists have designed foldable sound barriers by borrowing concepts from origami, the art of paper folding.
Mouse Models
Clearing the air on cilia development
24 May 2019A*STAR researchers have uncovered the sequence of genetic events behind the development of motile cilia in airways.
Molecular Biology
How cancer cells tip the Bim balance in their favor
24 May 2019Cancer cells evade Taxol-induced cell death by downregulating the expression of a protein known as BimEL.
Computational Modeling
Simulations shed light on air filter deployment
24 May 2019Using computational tools, A*STAR researchers are learning how best to deploy air treatment systems across large urban areas.
Heart Muscle Cells
Getting mature human heart muscle cells to multiply again
24 May 2019By triggering the Wnt signaling pathway, A*STAR scientists were able to reactivate proliferation in mature human heart muscle cells.
Immunology
Delivering a renewable source of Kupffer cells
24 May 2019A*STAR researchers have devised a method to generate a renewable source of mature human Kupffer cells for liver toxicity bioassays.
Nanotechnology
Towards thinner and faster transistors
24 May 2019Nanoribbon field effect transistors could usher in the next generation of computing.
A*STAR Singapore Immunology Network (A*STAR SIgN)
How bacteria influence host immunity
24 May 2019When parts of a bacteria's cell wall enter into circulation, its host experiences more severe autoimmune reactions.
Stem Cells
Growing a ‘spine’ on a chip
24 May 2019Microfluidic device allows for precise control of growth factor gradients, mimicking natural spinal cord development in vitro.
Skin Infection
Battling bacteria that get under the skin
23 May 2019A subset of skin-resident immune cells secrete the protein VEGFα to help mount a robust response to bacterial invasion.
Nanotechnology
Creating colors without dyes
23 May 2019Nanofabricated metallic structure arrays produce a kaleidoscope of bright colors.
A*STAR Singapore Immunology Network (A*STAR SIgN)
On the trail of two types of white blood cells
23 May 2019Nerve bundles and blood vessels each have their own specific subtypes of macrophages.