Infectious Diseases

A novel broad-spectrum drug candidate stalls replication of several SARS-CoV-2 variants and other coronaviruses, with the potential to boost preparedness against future pandemics.

A*STAR researchers uncover how bacterial hideouts created during tuberculosis infections can also protect and feed other opportunistic invaders.

A*STAR researchers develop a smarter delivery system for mRNA vaccines that boosts their targeting abilities and biological safety.

A unique RNA structure shared across SARS-CoV-2 variants may contribute to viral fitness, offering a potential target for new antiviral treatments.

Scientists identify a new, distinct group of the deadly yeast Candida auris, and urge the expansion of global surveillance efforts.

A*STAR researchers find that ordinary communications between immune cells during chikungunya virus infection can drive joint inflammation seen in the disease.

With near-real-time genomic monitoring, researchers catch emergent, treatment-evading SARS-CoV-2 mutations in immunocompromised patients with chronic infections.

Scientists survey how the mpox virus spreads through populations, the immunology of infections and current treatment interventions.

Vaccinated people affected by COVID-19 variants have different memory B cell responses than their close contacts who remain healthy.