A*STAR Singapore Immunology Network (A*STAR SIgN)

A melanoma drug is linked to long-term changes in the tumor environment in a subset of tumors that respond effectively to the drug

A vaccine against a devastating form of malaria common in Asia and South America is one step closer thanks to a long-awaited methodological advance

Chronic hepatitis B virus enhances liver cancer susceptibility by blocking a key DNA repair enzyme

T cells use a multi-pronged approach to promote an inflammatory counterattack against infectious threats

Vaccine development could be aided by increased understanding of the physical interactions between immune cells

The mechanism by which malaria parasites accumulate in the brain and other deep tissues of model mice has been identified

Structural analysis of the interaction between human leukocyte antigens and hepatitis B viruses reveals a path to better vaccine design

The antifolate drug methotrexate is highly potent against the malaria parasite Plasmodium vivax

Patients with chikungunya fever experience persistent joint pain because their body produces high amounts of pro-inflammatory cytokines

Three proteins work together to induce the production of an inflammatory factor in human immune cells

Antibodies derived from an individual who had previously been exposed to the Chikungunya virus raise hope of a new therapy

A subset of human immune cells monitors blood vessels for viral infection