A*STAR Singapore Immunology Network (A*STAR SIgN)

The infection of one dengue virus subtype can lead to the production of antibodies that confer protection against other dengue virus subtypes

Calicneurin inhibitors, used clinically as immunosuppressive drugs, are shown to confer a growth advantage to myeloid cells

Uric acid released from dying cells is a key driver of autoimmune diseases

The interaction between good and malignant immune cells may promote blood cancer invasiveness and progression

Chemotherapeutic drugs fight melanoma by attracting immune cells into tumors

A new molecular test for predicting liver cancer survival rates could lead to the development of improved immunotherapies

The inner layer of skin contains a population of immune cells specialized for fighting infection

Invading immune cells promote the growth and spread of primary tumors

Understanding the differences between various monocyte subtypes could aid diagnosis of blood disorders

A melanoma drug is linked to long-term changes in the tumor environment in a subset of tumors that respond effectively to the drug

A vaccine against a devastating form of malaria common in Asia and South America is one step closer thanks to a long-awaited methodological advance

Chronic hepatitis B virus enhances liver cancer susceptibility by blocking a key DNA repair enzyme