Highlights
HIV
A new approach to an old pandemic
6 July 2021The discovery of a new, highly conserved druggable site on the HIV reverse transcriptase could turn the tide in the wake of growing drug resistance.
A*STAR Institute Of Molecular And Cell Biology (A*STAR IMCB)
Opening the cellular gates to glucose
2 July 2021Low levels of sugar entering into pancreatic cells may be the culprit behind insulin secretion defects in early-onset diabetes.
A*STAR Singapore Immunology Network (A*STAR SIgN)
Figuring out one fever from another
30 June 2021A*STAR researchers identified immune markers that can distinguish between common febrile diseases in Saudi Arabia.
Institute Of Medical Biology (IMB)
NLRP1: How the body senses the common cold virus
28 June 2021The mysterious trigger of the NLRP1 inflammasome sensor has finally been identified: a protease found in the common cold-causing human rhinovirus tells our body that it has been invaded.
SARS-CoV-2
Comparing COVID-19 in children and adults
22 June 2021Understanding why COVID-19 tends to strike the old but spare the young could inform how to prioritize limited COVID-19 vaccines.
Polymers
Keeping it cool with polymer-encapsulated pigments
18 June 2021Encapsulating sun-blocking pigment particles within polymer shells can improve their ability to reflect light, leading to the enhanced cooling performance of coatings.
Carbon Dioxide
Controlling defects to capture more CO2
16 June 2021Defects are not necessarily bad; researchers have used them to improve the ability of molybdenum oxide thin films to capture CO2.
Institute Of Bioengineering And Nanotechnology (IBN)
Sifting out rare stem cells
14 June 2021Single-cell techniques have helped to identify a key molecular switch controlling how adult cells can be turned back to a stem cell-like state.
Manufacturing Trade And Connectivity (MTC)
When two are stronger than one
10 June 2021New research shows that titanium alloys joined by 3D-printed curved interlayers are stronger and less likely to crack.
Public Health
Getting ahead of dengue outbreaks
8 June 2021This two-step outbreak detection framework could give early warnings of dengue outbreaks, improving Singapore’s ability to control the disease.
Immunology
Deciphering a wound healing paradox
4 June 2021A*STAR researchers identify a novel mechanism in which an inflammatory protein heals wounds in healthy individuals but has the opposite effect in diabetics.
Inflammation
Getting granular about granulocyte differentiation
2 June 2021Controlling the delicate balance between immune cells called granulocytes and monocytes could make the difference between a healthy immune response and life-threatening sepsis.
Machine Learning
Piecing the cracks together
31 May 2021A hybrid approach combining deep learning with Bayesian inference has enabled more accurate, efficient and automatic crack detection.
